Article
Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus.
Glycobiology - 1 May 2010
Fang Wenxia, Ding Weiping, Wang Bin, Zhou Hui, Ouyang Haomiao, Ming Jia, Jin Cheng
Abstract excerpt
Protein O-mannosyltransferases (PMTs) initiate O-mannosylation of secretory proteins, which are of fundamental importance in eukaryotes. The human fungal pathogen Aspergillus fumigatus possesses three genes encoding for PMTs, namely, Afpmt1, Afpmt2 and Afpmt4. We have previously shown that lack o...
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