Article
Protein O-mannosylation is crucial for cell wall integrity, septation and viability in fission yeast.
Molecular microbiology - 1 Jul 2005
Willer Tobias, Brandl Martin, Sipiczki Matthias, Strahl Sabine
Abstract excerpt
Protein O-mannosyltransferases (PMTs) initiate the assembly of O-mannosyl glycans, which are of fundamental importance in eukaryotes. The PMT family, which is classified into PMT1, PMT2 and PMT4 subfamilies, is evolutionarily conserved. Despite the fact that PMTs are crucial for viability of baker's yeast as well as of mouse, recent studies suggested that there are significant differences in the organization and...
Topics
- Cell Proliferation
- Cell Wall
- Cloning, Molecular
- Gene Deletion
- Genes, Lethal
- Glycosylation
- Mannose
- Mannosyltransferases
- Metalloproteases
- Mutation
- Saccharomyces cerevisiae Proteins
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins