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Article

Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.

Diabetes care - 1 Oct 2008

Feng Yan, Mao Guangyun, Ren Xiaowei, Xing Houxun, Tang Genfu, Li Qiang, Li Xueqi, Sun Lirong, Yang Jinqui, Ma Weiqing, Wang Xiaobin, Xu Xiping

Abstract excerpt

OBJECTIVE: The purpose of this study was to investigate whether genetic variants could influence the antidiabetic efficacy of gliclazide in type 2 diabetic patients. RESEARCH DESIGN AND METHODS: A total of 1,268 type 2 diabetic patients whose diabetes was diagnosed within the past 5 years and who...

Read the complete abstract on PubMed

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Share to Amino Acid Substitution
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Glucose

Share to Diabetes Mellitus, Type 2

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Share to Potassium Channels, Inwardly Rectifying

Share to Receptors, Drug

Share to Sulfonylurea Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 18599530
DOI: 10.2337/dc07-2248
PMCID: PMC2551631

Genes

ABCC8
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18599530-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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