Article
Search for genetic determinants of sulfonylurea efficacy in type 2 diabetic patients from China.
Diabetologia - 1 Apr 2014
Ren Qian, Han Xueyao, Tang Yong, Zhang Xiuying, Zou Xiantong, Cai Xiaoling, Zhang Simin, Zhang Lihua, Li Hechao, Ji Linong
Abstract excerpt
AIMS/HYPOTHESIS: The aim of this study was to investigate whether genetic variance can influence the efficacy of glibenclamide in patients with type 2 diabetes. METHODS: A total of 747 patients with type 2 diabetes was enrolled from the Xiaoke Pills Clinical Trial, which is a double-blind, randomised controlled trial. All the patients had been treated with glibenclamide for 48 weeks, with strict drug dose...
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