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Article

ABCC8 polymorphism (Ser1369Ala): influence on severe hypoglycemia due to sulfonylureas.

Pharmacogenomics - 1 Dec 2010

Sato Ryosuke, Watanabe Hiroshi, Genma Rieko, Takeuchi Masahiro, Maekawa Masato, Nakamura Hirotoshi

Abstract excerpt

AIMS: Sulfonylureas are categorized according to their binding sites of the ATP-sensitive K+ channel (K(ATP) channel) complex in pancreatic β-cells. The binding sites are classified as A, B and A + B site (both A and B sites), respectively. The Ser1369Ala variant in the sulfonylurea receptor gene ABCC8 which encodes a subunit of the K(ATP) channel complex has been demonstrated to be associated with the...

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Source

Identifiers

PMID: 21142918
DOI: 10.2217/pgs.10.135

Genes

ABCC8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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ABCC8 polymorphism (Ser1369Ala): influence on severe hypoglycemia due to sulfonylureas.PMID 21142918Read ↗

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