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Article

Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes.

Acta pharmacologica Sinica - 1 Jan 2017

Li Qing, Tang Ting-Ting, Jiang Feng, Zhang Rong, Chen Miao, Yin Jun, Bao Yu-Qian, Cheng Xiang, Hu Cheng, Jia Wei-Ping

Abstract excerpt

KCNQ1 channel is a member of the voltage-gated potassium channel KQT-like subfamily. The KCNQ1 gene has recently been identified as a susceptibility locus for type 2 diabetes mellitus (T2DM). In the present study, we examined the effects of KCNQ1 variants on the therapeutic response to modified-release gliclazide (gliclazide MR) treatment in Chinese patients newly diagnosed with T2DM. A total of 100 newly...

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Identifiers

PMID: 27694910
DOI: 10.1038/aps.2016.103
PMCID: PMC5220536

Genes

KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes.PMID 27694910Read ↗

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