Article
CYP2C93 variant is associated with antidiabetes efficacy of gliclazide in Chinese type 2 diabetes patients.
Journal of diabetes investigation - 1 Sept 2016
Zeng Wotan, Guo Yali, Chen Peixian, Liu Zhike, Chen Dafang, Han Chunji
Abstract excerpt
AIMS/INTRODUCTION: The objective of the present study was to investigate the effects of CYP2C9*3 polymorphisms on the therapeutic response to gliclazide in type 2 diabetes patients. MATERIALS AND METHODS: A total of 746 incident type 2 diabetes patients were included in this study. After enrolment, patients went on 4-week gliclazide monotherapy. Fasting plasma glucose was measured before and after treatment....
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