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Article

The structural basis of chain length control in Rv1086.

Journal of molecular biology - 1 Aug 2008

Wang Wenjian, Dong Changjiang, McNeil Michael, Kaur Devinder, Mahapatra Sebabrata, Crick Dean C, Naismith James H

Abstract excerpt

In Mycobacterium tuberculosis, two related Z-prenyl diphosphate synthases, E,Z-farnesyl diphosphate synthase (Rv1086) and decaprenyl diphosphate synthase (Rv2361c), work in series to synthesize decaprenyl phosphate (C(50)) from isopentenyl diphosphate and E-geranyl diphosphate. Decaprenyl phosphate plays a central role in the biosynthesis of essential mycobacterial cell wall components, such as the...

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Identifiers

PMID: 18597781
DOI: 10.1016/j.jmb.2008.05.060
PMCID: PMC2527485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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