Article
Effect of the GC content of DNA on the distribution of UVB-induced bipyrimidine photoproducts.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology - 1 Jul 2008
Matallana-Surget Sabine, Meador Jarah A, Joux Fabien, Douki Thierry
Abstract excerpt
Solar UV radiation is a major mutagen that damages DNA through the formation of dimeric photoproducts between adjacent thymine and cytosine bases. A major effect of the GC content of the genome is thus anticipated, in particular in prokaryotes where this parameter significantly varies among species. We quantified the formation of UV-induced photolesions within both isolated and cellular DNA of bacteria of...
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