Article
Improvement of Saccharopolyspora spinosa and the kinetic analysis for spinosad production.
Applied biochemistry and biotechnology - 1 Mar 2009
Liang Yan, Lu Wenyu, Wen Jianping
Abstract excerpt
In this paper, a new spinosad-producing mutant UV-42-13 was obtained by employing rhamnose and sodium propionate resistant selection strategies in series with UV irradiation. Spinosad production of the mutant was 125.3 mg/L, improved 285.5% compared with that of the wild strain (32.5 mg/L).The results of experiment on tolerance of propyl alcohol addition showed that the tolerant ability to precursor was higher....
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