Article
A comparative metabolomics analysis of Saccharopolyspora spinosa WT, WH124, and LU104 revealed metabolic mechanisms correlated with increases in spinosad yield.
Bioscience, biotechnology, and biochemistry - 1 Jan 2013
Zhao Fanglong, Xue Chaoyou, Wang Meiling, Wang Xiaoyang, Lu Wenyu
Abstract excerpt
Metabolomics analysis of three Saccharopolyspora spinosa strains (wild type strain WT, ultraviolet mutant strain WH124, and metabolic engineering strain LU104) with different spinosad producing levels was performed by liquid chromatograph coupled to mass spectrometry (LC-MS). The metabolite profiles were subjected to hierarchal clustering analysis (HCA) and principal component analysis (PCA). The results of HCA...
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