Article
Compound mutagenesis boosts β-carotene biosynthesis in Neurospora crassa: ATP synthase mutation and enzymes activities enhancement.
Fungal genetics and biology : FG & B - 1 Dec 2025
He Yue, Huang Qian, Lyu Qingyang, Ji Gaosheng, Wang Xinhui, Yan Zhiying, Zhang Yijie, Li Xin, Tian Xueping
Abstract excerpt
Neurospora crassa is a kind of biosafe fungus capable of synthesizing β-carotene from diverse feedstocks. However, the yield is constrained by the capacity of N. crassa strain. To improve the β-carotene synthesis ability, ultraviolet (UV), chemical (diethyl sulfate), and heavy ion beam were integratively employed in this study to breed N. crassa strain with high β-carotene producing performance. A mutant N....
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