Article
Isopentenyl pyrophosphate-activated CD56+ {gamma}{delta} T lymphocytes display potent antitumor activity toward human squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2008
Alexander Alan A Z, Maniar Amudhan, Cummings Jean-Saville, Hebbeler Andrew M, Schulze Dan H, Gastman Brian R, Pauza C David, Strome Scott E, Chapoval Andrei I
Abstract excerpt
PURPOSE: The expression of CD56, a natural killer cell-associated molecule, on alphabeta T lymphocytes correlates with their increased antitumor effector function. CD56 is also expressed on a subset of gammadelta T cells. However, antitumor effector functions of CD56(+) gammadelta T cells are poorly characterized. EXPERIMENTAL DESIGN: To investigate the potential effector role of CD56(+) gammadelta T cells in...
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