Plasmacytoid dendritic cell subpopulations in head and neck squamous cell carcinoma.

doi:10.3892/or.2011.1350

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Article

Plasmacytoid dendritic cell subpopulations in head and neck squamous cell carcinoma.

Oncology reports - 1 Sept 2011

Thiel Annette, Kesselring Rebecca, Pries Ralph, Wittkopf Nadine, Puzik Alexander, Wollenberg Barbara

Abstract excerpt

Human plasmacytoid dendritic cells (PDCs) are present in solid tumor tissue and metastatic cervical lymph nodes (CLN) in head and neck squamous cell carcinoma (HNSCC). We recently showed that classical PDC functions are heavily disturbed in the tumor microenvironment. In this study we present a new approach to the subject by introducing 3 PDC subsets in HNSCC, characterized by the surface markers CD25, CD56 and...

Topics

Adolescent
Adult
Aged
Antigens, Differentiation
Biomarkers, Tumor
CD56 Antigen
Carcinoma, Squamous Cell
Cell Line, Tumor
Dendritic Cells
Head and Neck Neoplasms
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-2 Receptor alpha Subunit

Lectins, C-Type

Lymph Nodes

Lymphatic Metastasis

Membrane Glycoproteins

Middle Aged

Phenotype

Source

Open in PubMed

Identifiers

PMID: 21687955
DOI: 10.3892/or.2011.1350

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