Article
Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1.
BMC developmental biology - 1 Jul 2008
Keilani Serene, Sugaya Kiminobu
Abstract excerpt
BACKGROUND: Reelin and Notch-1 signaling pathways have been recently found to be necessary to induce the expression of brain lipid binding protein (BLBP) and to promote the process extension and the maturation of the neuronal progenitors, the radial glial cells. In this study, we report the cross talk between these two pathways. RESULTS: Both in vitro Reelin treatment and overexpression of Notch-1 intracellular...
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