Article
N-Glycosylation of the Drosophila neural protein Chaoptin is essential for its stability, cell surface transport and adhesive activity.
FEBS letters - 23 Jul 2008
Hirai-Fujita Yu, Yamamoto-Hino Miki, Kanie Osamu, Goto Satoshi
Abstract excerpt
Glycosylation of proteins can modulate their function in a striking variety of systems, including immune responses, neuronal activities and development. The Drosophila protein, Chaoptin (Chp), is essential for the development and maintenance of photoreceptor cells. This protein is heavily glycosylated, but the possible role of this glycosylation is not well-understood. Here we show that mutations introduced into...
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