Association of a single-nucleotide polymorphism in the promoter region of the VEGF gene with the risk of renal cell carcinoma.

doi:10.1089/gtmb.2011.0029

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Article

Association of a single-nucleotide polymorphism in the promoter region of the VEGF gene with the risk of renal cell carcinoma.

Genetic testing and molecular biomarkers - 1 Sept 2011

Ajaz Sadia, Khaliq Shagufta, Abid Aiysha, Hassan Asad Shehzad, Hashmi Altaf, Sultan Gauhar, Mohsin Rehan, Mubarrak Mohammad, Naqvi Syed Ali Anwar, Rizvi Syed Adib-ul-Hasan, Mehdi Syed Qasim

Abstract excerpt

AIMS: Vascular endothelial growth factor (VEGF) protein plays an important role in tumor development and progression. Polymorphisms in the VEGF gene may lead to over- or underexpression of the protein and may be associated with either risk or progression of malignancy. The aim of this case-control study is to identify and quantify the correlation between VEGF polymorphisms and renal cell carcinoma (RCC). RESULTS:...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma, Renal Cell
Case-Control Studies
Female
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Kidney Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Risk Factors

Vascular Endothelial Growth Factor A

Young Adult

Source

Open in PubMed

Identifiers

PMID: 21491998
DOI: 10.1089/gtmb.2011.0029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-21491998-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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