Article
No association between single nucleotide polymorphisms and the development of nephrotoxicity after orthotopic heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Jul 2008
Klauke Bärbel, Wirth Andreas, Zittermann Armin, Bohms Birte, Tenderich Gero, Körfer Reiner, Milting Hendrik
Abstract excerpt
BACKGROUND: Survival for heart transplantation (HTx) patients is limited by nephrotoxicity of the calcineurin inhibitors cyclosporine and tacrolimus. To determine whether genetic factors are involved in the development of renal dysfunction under immunosuppressive therapy, we screened various gene...
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