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Article

Renal failure after clinical heart transplantation is associated with the TGF-beta 1 codon 10 gene polymorphism.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Sept 2000

Baan C C, Balk A H, Holweg C T, van Riemsdijk I C, Maat L P, Vantrimpont P J, Niesters H G, Weimar W

Abstract excerpt

BACKGROUND: To determine whether genetic factors are involved in the development of renal dysfunction due to cyclosporine nephrotoxicity, we analyzed 2 polymorphisms in the signal sequence of the transforming growth factor (TGF)-beta 1 gene; codon 10 (Leu(10) --> Pro) and codon 25 (Arg(25) --> Pro). METHOD: Using sequence specific oligonucleotide probing, we analyzed both TGF-beta1 gene polymorphisms in cardiac...

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Identifiers

PMID: 11008076
DOI: 10.1016/s1053-2498(00)00155-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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