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Article

Chromatin regulation and gene centrality are essential for controlling fitness pleiotropy in yeast.

PloS one - 30 Nov 2009

Zhou Linqi, Ma Xiaotu, Arbeitman Michelle N, Sun Fengzhu

Abstract excerpt

BACKGROUND: There are a wide range of phenotypes that are due to loss-of-function or null mutations. Previously, the functions of gene products that distinguish essential from nonessential genes were characterized. However, the functions of products of non-essential genes that contribute to fitness remain minimally understood. PRINCIPAL FINDINGS: Using data from Saccharomyces cerevisiae, we investigated several...

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Identifiers

PMID: 19956643
DOI: 10.1371/journal.pone.0008086
PMCID: PMC2778950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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