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Article

Epigenetic regulation and the variability of gene expression.

Nature genetics - 1 Feb 2008

Choi Jung Kyoon, Kim Young-Joon

Abstract excerpt

We characterized the genetic variability of gene expression in terms of trans and cis variability for each yeast transcript. Genes that are highly regulated by nucleosomes showed a high degree of trans variability. From the expression profiles of mutants for various chromatin modifiers, we found that trans-variable genes are distinctly regulated at the chromatin level. The effect of chromatin regulators was...

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Source

Identifiers

PMID: 18227874
DOI: 10.1038/ng.2007.58

Genes

TBP
TAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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