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Article

Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 25 Jun 2008

Chen Zheng, Montcouquiol Mireille, Calderon Rene, Jenkins Nancy A, Copeland Neal G, Kelley Matthew W, Noben-Trauth Konrad

Abstract excerpt

The mouse cochlea emerges from the ventral pole of the otocyst to form a one and three-quarter coil. Little is known about the factors that control the growth of the cochlea. Jackson circler (jc) is a recessive mutation causing deafness resulting from a growth arrest of the cochlea duct at day 13.5 of embryonic development. Here, we identify the vertebrate homolog of the Drosophila Sobp (sine oculis-binding...

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Identifiers

PMID: 18579736
DOI: 10.1523/JNEUROSCI.1280-08.2008
PMCID: PMC2556235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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