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Article

Ush1c gene expression levels in the ear and eye suggest different roles for Ush1c in neurosensory organs in a new Ush1c knockout mouse.

Brain research - 30 Apr 2010

Tian Cong, Liu Xue Z, Han Fengchan, Yu Heping, Longo-Guess Chantal, Yang Bin, Lu Changjun, Yan Denise, Zheng Qing Y

Abstract excerpt

Usher syndrome (USH) is the most common form of deaf-blindness in humans. Molecular characterization revealed that the USH gene products form a macromolecular protein network in hair cells of the inner ear and in photoreceptor cells of the retina via binding to PDZ domains in the scaffold protein harmonin encoded by the Ush1c gene in mice and humans. Although several mouse mutants for the Ush1c gene have been...

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Identifiers

PMID: 20211154
DOI: 10.1016/j.brainres.2010.02.079
PMCID: PMC2907663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ush1c gene expression levels in the ear and eye suggest different roles for Ush1c in neurosensory organs in a new Ush1c knockout mouse.PMID 20211154Read ↗

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