Article
Ush1c gene expression levels in the ear and eye suggest different roles for Ush1c in neurosensory organs in a new Ush1c knockout mouse.
Brain research - 30 Apr 2010
Tian Cong, Liu Xue Z, Han Fengchan, Yu Heping, Longo-Guess Chantal, Yang Bin, Lu Changjun, Yan Denise, Zheng Qing Y
Abstract excerpt
Usher syndrome (USH) is the most common form of deaf-blindness in humans. Molecular characterization revealed that the USH gene products form a macromolecular protein network in hair cells of the inner ear and in photoreceptor cells of the retina via binding to PDZ domains in the scaffold protein...
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