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Article

Genetic diversity patterns at the human clock gene period 2 are suggestive of population-specific positive selection.

European journal of human genetics : EJHG - 1 Dec 2008

Cruciani Fulvio, Trombetta Beniamino, Labuda Damian, Modiano David, Torroni Antonio, Costa Rodolfo, Scozzari Rosaria

Abstract excerpt

Period 2 (PER2) is a key component of the mammalian circadian clock machinery. In humans, genetic variation of clock genes or chronic disturbance of circadian rhythmicity has been implied in the onset of several phenotypes, ranging from periodic insomnias to advanced or delayed sleep phases, to m...

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Identifiers

PMID: 18575464
DOI: 10.1038/ejhg.2008.105

Genes

PER2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18575464-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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