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Article

Methylenetetrahydrofolate reductase (MTHFR) C677T genetic polymorphism and late infarct-related coronary artery patency after thrombolysis.

Journal of thrombosis and thrombolysis - 1 May 2009

Patti Giuseppe, Fossati Carolina, Nusca Annunziata, Mega Simona, Pasceri Vincenzo, D'Ambrosio Andrea, Giannetti Barbara, Annibali Ombretta, Avvisati Giuseppe, Di Sciascio Germano

Abstract excerpt

In patients with acute myocardial infarction (AMI), a persistently occluded infarct-related artery (IRA) is associated with unfavorable prognosis and genetic factors may be contributing factors to thrombolysis failure. One-hundred and one consecutive patients treated with intravenous thrombolysis during AMI were blind-tested for methylenetetrahydrofolate reductase (MTHFR) and circulating homocysteine levels and...

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Identifiers

PMID: 18574671
DOI: 10.1007/s11239-008-0235-9

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Methylenetetrahydrofolate reductase (MTHFR) C677T genetic polymorphism and late infarct-related coronary artery patency after thrombolysis.PMID 18574671Read ↗

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