Article
Homozygosity of the TT methylenetetrahydrofolate reductase C677T genotype is an independent long-term predictor of cardiac death in patients with premature myocardial infarction.
Current medical research and opinion - 1 Jul 2021
Rallidis Loukianos S, Kosmas Nikolaos, Stathopoulou Eleni, Rallidi Maria, Gialeraki Argyri
Abstract excerpt
BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is the main genetic modulator of homocysteine. Data suggest a potential association of homozygosity for the TT MTHFR genotype with premature myocardial infarction (MI). We explored whether TT homozygosity is associated with long-term prognosis in patients with premature ST-segment elevation MI (STEMI). METHODS: A total of 265 consecutive...
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