Article
Methylenetetrahydrofolate reductase gene and coronary artery disease.
Circulation - 7 Jan 1997
van Bockxmeer F M, Mamotte C D, Vasikaran S D, Taylor R R
Abstract excerpt
BACKGROUND: Hypermocysteinemia has been substantiated as a risk factor for occlusive vascular disease. A common mutation (nucleotide 677 C-->T) has been described recently in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, which results in a valine for alanine substitution, a thermolab...
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