Article
Pharacogenetic effects of dopamine transporter gene polymorphisms on response to chlorpromazine and clozapine and on extrapyramidal syndrome in schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 16 Aug 2010
Xu Mingqing, Xing Qinghe, Li Sheng, Zheng Yonglan, Wu Shengnan, Gao Rui, Yu Lan, Guo Tingwei, Yang Yifeng, Liu Jixia, Zhang Aiping, Zhao Xinzhi, He Guang, Zhou Jian, Wang Lei, Xuan Jiekun, Du Jing, Li Xingwang, Feng Guoyin, Lin Zhiguang, Xu Yifeng, St Clair David, Lin Zhicheng, He Lin
Abstract excerpt
A number of studies have investigated the effectiveness of the dopamine transporter (SLC6A3) Gene as an antipsychotic target. However, the focus has mainly been on a 40-bp variable number of a tandem repeat (VNTR) in the 3'-region and results have been inconsistent. To fully evaluate SLC6A3 as a...
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