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Article

Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1.

Experimental eye research - 1 Aug 2008

Bhattacharjee Partha S, Neumann Donna M, Foster Timothy P, Bouhanik Saadallah, Clement Christian, Vinay Dass, Thompson Hilary W, Hill James M

Abstract excerpt

The isoform-specific role of human apolipoprotein E (apoE) has been assessed in a mouse model of ocular herpes. Female, age-matched transgenic mice knocked-in for the human allele apoE3 or apoE4 and their parent C57Bl/6 mice were inoculated corneally with HSV-1 strain KOS. Ocular HSV-1 pathogenesis was monitored through viral replication and clinical progression of stromal opacity and neovascularization by...

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Share to Apolipoproteins E
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18572164
DOI: 10.1016/j.exer.2008.05.007
PMCID: PMC2566951

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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