Article
Genetic factors in autoimmune myasthenia gravis.
Annals of the New York Academy of Sciences - 1 Jan 2008
Giraud Matthieu, Vandiedonck Claire, Garchon Henri-Jean
Abstract excerpt
Autoimmune myasthenia gravis (MG) is a multifactorial disease, markedly influenced by genetic factors, even though it shows limited heritability. The clinically typical form of autoimmune MG with thymus hyperplasia shows the most reproducible genetic associations, especially with the A1-B8-DR3 (8.1) haplotype of the major histocompatibility complex (MHC). However, because of strong linkage disequilibrium, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
