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Article

Regulation of CD163 associated casein kinase II activity is haptoglobin genotype dependent.

Molecular and cellular biochemistry - 1 Oct 2008

Strauss Merav, Levy Andrew P

Abstract excerpt

Free hemoglobin is now recognized as a major mediator of a variety of vascular diseases. The abundant serum protein haptoglobin irreversibly binds to hemoglobin and promotes the uptake of hemoglobin via the macrophage CD163 receptor. The haptoglobin gene is polymorphic in man with two common alleles denoted 1 and 2. The haptoglobin genotype specifies the nature of the response of the macrophage to free...

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Share to Alkaline Phosphatase
Share to Antigens, Differentiation, Myelomonocytic
Share to Casein Kinase II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD163 Antigen

Share to Haptoglobins

Share to Hemoglobins

Share to Immunoprecipitation

Share to Leukocytes, Mononuclear

Source

Identifiers

PMID: 18563533
DOI: 10.1007/s11010-008-9840-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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