Study of the association between the CAPSL-IL7R locus and type 1 diabetes.

doi:10.1007/s00125-008-1070-4

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Study of the association between the CAPSL-IL7R locus and type 1 diabetes.

Diabetologia - 1 Sept 2008

Santiago J L, Alizadeh B Z, Martínez A, Espino L, de la Calle H, Fernández-Arquero M, Figueredo M A, de la Concha E G, Roep B O, Koeleman B P C, Urcelay E

Abstract excerpt

AIMS/HYPOTHESIS: In the past few years, several genes outside the MHC region have been described as new susceptibility genetic factors to type 1 diabetes. An association between CAPSL-rs1445898 and type 1 diabetes was reported in a large white population and corroborated in a genome-wide analysis, which also found an association with IL7R, which is located adjacent to CAPSL. The aim of this study was to replicate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Age of Onset

Share to Child

Share to Diabetes Mellitus, Type 1

Share to Genome, Human

Share to Polymorphism, Single Nucleotide

Share to Receptors, Interleukin-7

Share to Reference Values

Source

Open in PubMed

Identifiers

PMID: 18563381
DOI: 10.1007/s00125-008-1070-4

Genes

CAPSL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Study of the association between the CAPSL-IL7R locus and type 1 diabetes.PMID 18563381Read ↗

TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes.Semantic proximity Read ↗

Clinical signs of type 1 diabetes are associated with type 2 diabetes marker transcription factor 7-like 2 polymorphism.Semantic proximity Read ↗

Association of variants of the TCF7L2 gene with increases in the risk of type 2 diabetes and the proinsulin:insulin ratio in the Spanish population.Semantic proximity Read ↗

TCF7L2 polymorphism a prominent marker among subjects with Type-2-Diabetes with a positive family history of diabetes.Semantic proximity Read ↗

The type 2 diabetes-associated variant in TCF7L2 is associated with latent autoimmune diabetes in adult Europeans and the gene effect is modified by obesity: a meta-analysis and an individual study.Semantic proximity Read ↗

CTLA4+49G allele associates with early onset of type 1 diabetes in North Indians.Semantic proximity Read ↗

A replication study of the IRS1, CAPN10, TCF7L2, and PPARG gene polymorphisms associated with type 2 diabetes in two different populations of Mexico.Semantic proximity Read ↗

Interleukin-7 and soluble Interleukin-7 receptor levels in type 1 diabetes - Impact of IL7RA polymorphisms, HLA risk genotypes and clinical features.Semantic proximity Read ↗

Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-CellsSemantic proximity Read ↗

Expression of B7 and CD28 family genes in newly diagnosed type 1 diabetes.Semantic proximity Read ↗

The Association Between Circulating Levels of miRNA‐181a and Pancreatic Beta Cells Dysfunction via SMAD7 in Type 1 Diabetic Children and AdolescentsSemantic proximity Read ↗

IL-7R gene variants are associated with breast cancer susceptibility in Chinese Han women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.