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Article

TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes.

Diabetes care - 1 Feb 2018

Redondo Maria J, Geyer Susan, Steck Andrea K, Sosenko Jay, Anderson Mark, Antinozzi Peter, Michels Aaron, Wentworth John, Xu Ping, Pugliese Alberto

Abstract excerpt

OBJECTIVE: The phenotypic diversity of type 1 diabetes suggests heterogeneous etiopathogenesis. We investigated the relationship of type 2 diabetes-associated transcription factor 7 like 2 (TCF7L2) single nucleotide polymorphisms (SNPs) with immunologic and metabolic characteristics at type 1 diabetes diagnosis. RESEARCH DESIGN AND METHODS: We studied TrialNet participants with newly diagnosed autoimmune type 1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29025879
DOI: 10.2337/dc17-0961
PMCID: PMC5780048

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TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes.PMID 29025879Read ↗

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