Article
A replication study of the IRS1, CAPN10, TCF7L2, and PPARG gene polymorphisms associated with type 2 diabetes in two different populations of Mexico.
Annals of human genetics - 1 Sept 2011
Martínez-Gómez Laura E, Cruz Miguel, Martínez-Nava Gabriela A, Madrid-Marina Vicente, Parra Esteban, García-Mena Jaime, Espinoza-Rojo Mónica, Estrada-Velasco Barbara I, Piza-Roman Luis F, Aguilera Penelope, Burguete-García Ana I
Abstract excerpt
Type 2 diabetes (T2D) is a chronic degenerative disease that involves the participation of several genetic and environmental factors. The objective of the study was to determine the association of the IRS1 (rs1801278), CAPN10 (rs3792267), TCF7L2 (rs7903146 and rs12255372), and PPARG (rs1801282) gene polymorphisms with T2D, in two different Mexican populations. We conducted a case-control replication study in the...
