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Article

Structure-function relationship of bifunctional scorpion toxin BmBKTx1.

Acta biochimica et biophysica Sinica - 1 Nov 2008

Wang Suming, Huang Lijun, Wicher Dieter, Chi Chengwu, Xu Chenqi

Abstract excerpt

As the first identified scorpion toxin active on both big conductance Ca2+-activated K+ channels (BK) and small conductance Ca2+-activated K+ channels (SK), BmBKTx1 has been proposed to have two separate functional faces for two targets. To investigate this hypothesis, two double mutants, K21A-Y30A and R9A-K11A, together with wild-type toxin were expressed in Escherichia coli. The recombinant toxins were tested...

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Source

Identifiers

PMID: 18989577
DOI: 10.1111/j.1745-7270.2008.00479.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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