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Predictive value of CD44 and CD24 for prognosis and chemotherapy response in invasive breast ductal carcinoma.

International journal of clinical and experimental pathology - 1 Jan 2015

Chen Yanping, Song Jinlian, Jiang Yuhong, Yu Chundong, Ma Zhongliang

Abstract excerpt

OBJECTIVE: Cells with unique phenotypes and stem cell-like properties have been found to exist in breast cancer. The aim of the present study was to study the relationship of CD24, CD44, CD44(+)/CD24(-/low) and CD44(-)/CD24(+) tumor phenotypes' with clinico-pathological features, chemotherapy response and with prognosis. METHODS: The study included paraffin-embedded tissues of 140 primary and secondary invasive...

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Carcinoma, Ductal, Breast
CD24 Antigen
Chemotherapy, Adjuvant
Hyaluronan Receptors
Lymphatic Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Recurrence, Local

Proportional Hazards Models

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PMID: 26617852
PMCID: PMC4637668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Predictive value of CD44 and CD24 for prognosis and chemotherapy response in invasive breast ductal carcinoma.PMID 26617852Read ↗

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The distribution of CD44+/CD24- cancer stem cells in breast cancer and its relationship with prognostic factors.Semantic proximity Read ↗

CD44(+)/CD24(-) cells are transit progenitors and do not determine the molecular subtypes and clinical parameters in breast carcinomas.Semantic proximity Read ↗

CD44+/CD24‑ phenotype predicts a poor prognosis in triple‑negative breast cancerSemantic proximity Read ↗

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The CD44+/CD24- phenotype is enriched in basal-like breast tumors.Semantic proximity Read ↗

Cancer stem cell markers ALDH1 and CD44+/CD24- phenotype and their prognosis impact in invasive ductal carcinomaSemantic proximity Read ↗

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Enriched CD44(+)/CD24(-) population drives the aggressive phenotypes presented in triple-negative breast cancer (TNBC).Semantic proximity Read ↗

The CD44+/CD24- phenotype relates to 'triple-negative' state and unfavorable prognosis in breast cancer patients.Semantic proximity Read ↗

Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics.Semantic proximity Read ↗

Are CD44+/CD24- cells the assumed cancer stem cells in breast cancer?Semantic proximity Read ↗

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