Article
Functional IL-18 promoter gene polymorphisms in Tunisian nasopharyngeal carcinoma patients.
Cytokine - 1 Aug 2008
Farhat Karim, Hassen Elham, Bouzgarrou Nadia, Gabbouj Sallouha, Bouaouina Noureddine, Chouchane Lotfi
Abstract excerpt
OBJECTIVES: There is growing evidence suggesting that IL-18 levels may affect individual to virus-associated neoplasia and that single nucleotide polymorphisms (SNPs) within the gene may influence its production. In this study we wanted to know whether IL-18 polymorphisms at positions -607 C/A and -137 G/A are associated with susceptibility and/or are markers of nasopharyngeal carcinoma (NPC) prognosis. METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
