Article
Association of IL-12p40 +1188 A/C polymorphism with nasopharyngeal cancer risk and tumor extension.
Tissue antigens - 1 Aug 2011
Ben Chaaben A, Busson M, Douik H, Boukouaci W, Mamoghli T, Chaouch L, Harzallah L, Dorra S, Fortier C, Ghanem A, Charron D, Krishnamoorthy R, Guemira F, Tamouza R
Abstract excerpt
The interleukin 12 (IL-12) cytokine, encoded by polymorphic genes, plays a central role in the T helper 1 cell-mediated immunity against tumors. We investigated whether the 3' untranslated region +1188 A/C polymorphism (rs 3212227) influences the nasopharyngeal carcinoma (NPC) risk in Tunisian pa...
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