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Article

Dopamine transporter polymorphism modulates oculomotor function and DAT1 mRNA expression in schizophrenia.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2009

Wonodi Ikwunga, Hong L Elliot, Stine O Colin, Mitchell Braxton D, Elliott Amie, Roberts Rosalinda C, Conley Robert R, McMahon Robert P, Thaker Gunvant K

Abstract excerpt

Smooth pursuit eye movement (SPEM) deficit is an established schizophrenia endophenotype with a similar neurocognitive construct to working memory. Frontal eye field (FEF) neurons controlling SPEM maintain firing when visual sensory information is removed, and their firing rates directly correlate with SPEM velocity. We previously demonstrated a paradoxical association between a functional polymorphism of...

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Share to Dopamine Plasma Membrane Transport Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 18553389
DOI: 10.1002/ajmg.b.30811
PMCID: PMC2774755

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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