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Article

Genetic associations with hypoxemia and pulmonary arterial pressure in COPD.

Chest - 1 Mar 2009

Castaldi Peter J, Hersh Craig P, Reilly John J, Silverman Edwin K

Abstract excerpt

BACKGROUND: Hypoxemia, hypercarbia, and pulmonary arterial hypertension are known complications of advanced COPD. We sought to identify genetic polymorphisms associated with these traits in a population of patients with severe COPD from the National Emphysema Treatment Trial (NETT). METHODS: In 389 participants from the NETT Genetics Ancillary Study, single-nucleotide polymorphisms (SNPs) were genotyped in five...

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Topics

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Share to Epoxide Hydrolases
Share to Amyloid beta-Protein Precursor
Share to Hypertension, Pulmonary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoxia

Share to Linkage Disequilibrium

Share to Pulmonary Disease, Chronic Obstructive

Share to Pulmonary Surfactant-Associated Protein B

Share to Receptors, Cell Surface

Source

Open in PubMed Open full text

Identifiers

PMID: 19017876
DOI: 10.1378/chest.08-1993
PMCID: PMC2906241

Genes

EPHX1
SERPINE2
SFTPB
GSTP1
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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