Article
Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis.
Human genetics - 1 Nov 2003
Selman Moises, Lin Hung-Mo, Montaño Martha, Jenkins Audrey L, Estrada Andrea, Lin Zhenwu, Wang Guirong, DiAngelo Susan L, Guo Xiaoxuan, Umstead Todd M, Lang C Max, Pardo Annie, Phelps David S, Floros Joanna
Abstract excerpt
Derangement in pulmonary surfactant or its components and alveolar collapse are common findings in idiopathic pulmonary fibrosis (IPF). Surfactant proteins play important roles in innate host defense and normal function of the lung. We examined associations between IPF and genetic polymorphic var...
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