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Article

Genetic association analysis of COPD candidate genes with bronchodilator responsiveness.

Respiratory medicine - 1 Apr 2009

Kim Woo Jin, Hersh Craig P, DeMeo Dawn L, Reilly John J, Silverman Edwin K

Abstract excerpt

Airflow limitation in COPD patients is not fully reversible. However, there may be large variability in bronchodilator responsiveness (BDR) among COPD patients, and familial aggregation of BDR suggests a genetic component. Therefore, we investigated the association between six candidate genes and BDR in subjects with severe COPD. A total of 389 subjects from the National Emphysema Treatment Trial (NETT) were...

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Source

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Identifiers

PMID: 19111454
DOI: 10.1016/j.rmed.2008.10.025
PMCID: PMC2745950

Genes

FEV
EPHX1
ADRB2
GSTP1
SERPINE2
SFTPB
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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