Article
Genomic location and characterisation of MIC genes in cattle.
Immunogenetics - 1 Aug 2008
Birch James, De Juan Sanjuan Cristina, Guzman Efrain, Ellis Shirley A
Abstract excerpt
Major histocompatibility complex (MHC) class I chain-related (MIC) genes have been previously identified and characterised in human. They encode polymorphic class I-like molecules that are stress-inducible, and constitute one of the ligands of the activating natural killer cell receptor NKG2D. We have identified three MIC genes within the cattle genome, located close to three non-classical MHC class I genes. The...
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