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Article

A transcription factor regulatory cascade controls secreted aspartic protease expression in Candida albicans.

Molecular microbiology - 1 Aug 2008

Dabas Neelam, Morschhäuser Joachim

Abstract excerpt

Secreted aspartic proteases (Saps) contribute to the virulence of Candida albicans, a major fungal pathogen of humans. One function of the Saps, which is specifically mediated by the Sap2p isoenzyme, is the degradation of proteins for use as a nitrogen source. The utilization of alternative nitrogen sources in fungi is controlled by GATA transcription factors and we found that C. albicans mutants lacking the GATA...

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Identifiers

PMID: 18547391
DOI: 10.1111/j.1365-2958.2008.06297.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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