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Article

Transcriptome Analysis Unveils Gln3 Role in Amino Acids Assimilation and Fluconazole Resistance in Candida glabrata.

Journal of microbiology and biotechnology - 28 May 2021

Pérez-de Los Santos Francisco J, García-Ortega Luis Fernando, Robledo-Márquez Karina, Guzmán-Moreno Jesús, Riego-Ruiz Lina

Abstract excerpt

After Candida albicans, Candida glabrata is one of the most common fungal species associated with candidemia in nosocomial infections. Rapid acquisition of nutrients from the host is important for the survival of pathogens which possess the metabolic flexibility to assimilate different carbon and nitrogen compounds. In Saccharomyces cerevisiae, nitrogen assimilation is controlled through a mechanism known as...

Topics

ATP-Binding Cassette Transporters
Amino Acids
Ammonium Compounds
Antifungal Agents
Candida glabrata
Catabolite Repression
Drug Resistance, Fungal
Fluconazole
Fungal Proteins
GATA Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Profiling

Gene Expression Regulation, Fungal

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 33879640
DOI: 10.4014/jmb.2012.12034
PMCID: PMC9705932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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