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Article

Tetracycline-inducible expression of individual secreted aspartic proteases in Candida albicans allows isoenzyme-specific inhibitor screening.

Antimicrobial agents and chemotherapy - 1 Jan 2008

Staib Peter, Lermann Ulrich, Blass-Warmuth Julia, Degel Björn, Würzner Reinhard, Monod Michel, Schirmeister Tanja, Morschhäuser Joachim

Abstract excerpt

The yeast Candida albicans possesses a gene family that encodes secreted aspartic proteases (Saps), which are important for the virulence of this human fungal pathogen. Inhibitors of the Saps could therefore be used as novel antimycotic agents for the treatment of C. albicans infections. In the p...

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Identifiers

PMID: 17954688
DOI: 10.1128/AAC.01072-07
PMCID: PMC2223888

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17954688-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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