Article
Skeletal muscle-specific ablation of gamma(cyto)-actin does not exacerbate the mdx phenotype.
PloS one - 11 Jun 2008
Prins Kurt W, Lowe Dawn A, Ervasti James M
Abstract excerpt
We previously documented a ten-fold increase in gamma(cyto)-actin expression in dystrophin-deficient skeletal muscle and hypothesized that increased gamma(cyto)-actin expression may participate in an adaptive cytoskeletal remodeling response. To explore whether increased gamma(cyto)-actin fortifies the cortical cytoskeleton in dystrophic skeletal muscle, we generated double knockout mice lacking both dystrophin...
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