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Article

Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli.

The Journal of antimicrobial chemotherapy - 1 Sept 2008

Sandegren Linus, Lindqvist Anton, Kahlmeter Gunnar, Andersson Dan I

Abstract excerpt

OBJECTIVES: The biological fitness cost of antibiotic resistance is a key parameter in determining the rate of appearance and spread of antibiotic-resistant bacteria. We identified mutations conferring nitrofurantoin resistance and examined their effect on the fitness of clinical Escherichia coli isolates. METHODS: By plating bacterial cells on agar plates containing nitrofurantoin, spontaneous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18544599
DOI: 10.1093/jac/dkn222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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