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Article

Biological costs and mechanisms of fosfomycin resistance in Escherichia coli.

Antimicrobial agents and chemotherapy - 1 Sept 2003

Nilsson Annika I, Berg Otto G, Aspevall Olle, Kahlmeter Gunnar, Andersson Dan I

Abstract excerpt

Fosfomycin is a cell wall inhibitor used mainly for the treatment of uncomplicated lower urinary tract infections. As shown here, resistance to fosfomycin develops rapidly in Escherichia coli under experimental conditions, but in spite of the relatively high mutation rate in vitro, resistance in...

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Identifiers

PMID: 12936984
DOI: 10.1128/AAC.47.9.2850-2858.2003
PMCID: PMC182645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12936984-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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