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Article

Prediction of nitrofurantoin resistance among Enterobacteriaceae and mutational landscape of in vitro selected resistant Escherichia coli.

Research in microbiology - 1 Jan 2000

Khamari Balaram, Adak Sudeshna, Chanakya Pachi Pulusu, Lama Manmath, Peketi Arun Sai Kumar, Gurung Saurav Anand, Chettri Sushil, Kumar Prakash, Bulagonda Eswarappa Pradeep

Abstract excerpt

Nitrofurantoin (NIT) has long been a drug of choice in the treatment of lower urinary tract infections. Recent emergence of NIT resistant Enterobacteriaceae is a global concern. An ordinal logistic regression model based on PCR amplification patterns of five genes associated with NIT resistance (nfsA, nfsB, ribE, oqxA, and oqxB) among 100 clinical Enterobacteriaceae suggested that a combination of oqxB, nfsB,...

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PMID: 34718096
DOI: 10.1016/j.resmic.2021.103889

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